Information on ratio of glia to neurons

During the lecture on BigBrain anatomy for beginners there was a question concerning the proportion between the two kinds of cells found in brain tissue: glial cells and neurons.
Very many text books state that the human brain has a glia:neuron ratio of 10:1. But they never provide a reference to underpin this information!
The group of Suzana Herculano-Houzel published a very nice article ( on the numerical relationship between neuronal and non-neuronal (i.e. glial) cells in the human brain.

1 Like

ha! interesting. So it’s mainly because there’s very few neurones in the white matter, and then there’s this huge, exponentially growing region, composed mostly of non-neuronal cells. Thank you! :pray: